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Shop Valacyclovir (Valtrex) or Acyclovir, and Acyclovir cream

The Duo

Double trouble treatment for cold sores

The only prescription Cold Sore treatment stronger than oral Acyclovir? Oral Acyclovir + Acyclovir cream. This dynamic duo busts outbreaks as soon as they start. Manage your prescription online and get meds delivered free to your home with wisp.


Double your defense against Cold Sore outbreaks with prescription antivirals that reduce the frequency and severity of symptoms. Oral herpes—a.k.a. Cold Sores—caused by the Herpes Simplex Virus, are blisters that form around the mouth. Outbreaks sometimes consist of just one Cold Sore, but often produce a cluster of painful ulcers. Experiencing several herpes outbreaks a year or more typically depends on the total number of previous outbreaks, as well as how quickly an antiviral (Valacyclovir or Acyclovir) is administered.

Read more about Cold Sores

The essentials

-- Reviews


Cold sores are common. But outbreaks are easily decreased in intensity and duration with antiviral medication. We prescribe FDA approved meds based on the frequency and severity of symptoms.

—Dr Mary Clifton

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