Question 1

Do I need a prescription for GHK-Cu Topical Cream?

Accepted Answer

Yes, our GHK-Cu Topical Cream is only available with a prescription from a provider.

Question 2

How is this different from other copper peptide serums?

Accepted Answer

Most OTC copper peptide serums contain GHK-Cu at concentrations between 0.1% and 0.3%. At 0.5%, this formulation delivers a prescription dose of the active peptide—the level used in clinical research demonstrating visible improvements in skin laxity, firmness, fine lines, and density. It’s also a cream rather than a serum, providing a richer delivery format suited to both face and eye use.

Question 3

Can I use GHK-Cu Cream with my existing skincare routine?

Accepted Answer

Yes—GHK-Cu Topical Cream is designed to complement, not replace, your existing regimen. If you use a retinoid, an alternate-night protocol works well: retinoid one night, GHK-Cu the next. Both support collagen and skin renewal through different mechanisms, making them a well-matched pairing. GHK-Cu should also be layered with moisturizers and SPF as part of your daytime routine.

Question 4

Does GHK-Cu Cream have side effects?

Accepted Answer

Common side effects: Mild skin irritation or redness at application site (typically resolves within 1–2 weeks)—alternate application days to help reduce irritation Temporary tingling sensation upon application Uncommon side effects: Allergic contact dermatitis (rare — discontinue use if persistent rash develops) Do not use GHK-Cu if you have: A known allergy to copper peptides or any excipient in the formulation Active skin infections, open wounds, or compromised skin barrier at application site Wilson's disease (copper metabolism disorder) Other copper storage or processing disorders This is not a complete list of risks and side effects, and others may occur. If symptoms worsen or you notice signs of an allergic reaction, contact a provider right away.

GHK-Cu Topical Cream (0.5%)

GHK-Cu Topical Cream (0.5%)