Hands holding red paper cut-out of urinary tract system on purple background

The Best Daily UTI Prevention

By Simona Byler
August 2, 2024

Urinary tract infections (UTIs) are one of the most common infectious diseases worldwide—and they’re especially common for women. About one-third of women will have a significant UTI by the time they’re 24 and about half will have at least one UTI in their lifetime (1). In our book, that’s gotta change! That’s why we’re here to talk about taking the best daily supplements for UTI prevention—so you can stop that awful burning and “gotta go” feeling before it starts!

While there are plenty of home remedies for UTIs, we’re happy to announce that supplements with anti-inflammatory ingredients, antioxidants, and D-mannose can actually make a difference in your urinary tract health. With that in mind, read on to learn all about D-mannose benefits (many!), side effects (few!), and how certain daily supplements can help keep you UTI-free.

What is D-mannose?

D-mannose is a type of sugar that is closely related to glucose. A few different fruits naturally have D-mannose in high amounts, including apples, oranges, peaches, and you guessed it, cranberries! But, taking D-mannose in a supplement form is a wayyyy better and more effective method to combat UTIs than chugging cranberry juice—trust us. D-mannose is easy to access, safe for most adults, and a great alternative to taking preventative antibiotics if you’re struggling with recurring UTIs.

Wondering how a kind of simple sugar can possibly help you prevent UTIs? Well, unlike other sugars, your body doesn’t metabolize D-mannose quickly. Instead, it makes its way through your system, into your kidneys, and then flushes out through your urinary tract. And what does it flush out with it? All that nasty, infection-causing bacteria, of course!

Benefits of D-mannose include:

  • It’s a promising natural supplement: There are plenty of natural remedies for UTIs out there—and some are better than others! D-mannose is a natural option with several studies reporting that it’s effective for preventing recurring UTIs and treating uncomplicated infections (2).
  • It’s a good alternative to antibiotics: If you have a raging UTI, you should deffo take antibiotics to kill those bad bacteria! The thing is, antibiotics kill off the good bacteria, too. When taken early enough, D-mannose specifically targets common, UTI-causing bacteria—without harming the good bacteria or causing antibiotic resistance.
  • It’s easy to access and use: Need we say more? D-mannose is an ingredient in UTI cleanse powders and daily preventative supplements to help you keep UTIs from ruining your day.

How does D-mannose work?

Alright, let’s talk about how taking D-mannose for UTI prevention actually works. Kinda gross but interesting fact: about 90 percent of UTIs are caused by E. coli bacteria (1). When E. coli makes its way into your urinary tract—from frequent sex, wet bathing suits, and other usual culprits—it does what all bad bacteria do best: multiply rapidly and cause infections.

While E. coli can multiply quickly, it takes some time to stick to the lining of your urinary tract and bladder. That’s where D-mannose can help! Once you’ve taken D-mannose, it filters through your system to your urinary tract. There, it can grab onto and sugar-coat the free-floating E. coli bacteria. Then, you flush both D-mannose and E. coli out of your body when you pee!

E. coli is always present in certain parts of your system—but it shouldn’t make itself at home in your urinary tract. Taking D-mannose for UTI prevention is an easy and effective way to keep this bacteria from sticking around and causing an infection.

Are there side effects for
D-mannose?

Most folks won’t experience side effects when taking D-mannose for UTI prevention. But, everyone’s system reacts differently! Possible D-mannose side effects include bloating, loose stools, or diarrhea. These side effects are usually mild and tend to resolve on their own as your body adjusts.

There are concerns that D-mannose can harm your kidneys if taken at very high doses. So, always follow the recommended dosage and directions to avoid any potential adverse effects. Because it’s a type of sugar, make sure you proceed with caution when taking D-mannose if you have diabetes—talk with a doctor and monitor your blood sugar closely. Final note: D-mannose is not recommended during pregnancy, since high doses may lead to birth defects.



A glass pill jar of UTI antibiotics to treat urinary tract infections on a pink background and red surface

UTI Antibiotics

Prescription antibiotics used to prevent & treat Urinary Tract Infections.

Starting at $65.00

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Bottle of D-Mannose to treat UTI on a red surface, on a pink background

D-Mannose Capsules

Over-the-counter UTI defense—maintain bladder health and naturally prevent UTIs.

Starting at $27.00

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Wisp Daily Urinary Support Capsules on a red surface with a pink background

Daily Urinary Tract Support Capsules

Defend against recurrent UTIs and painful symptoms with daily urinary support.

Starting at $51.00

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Wisp Urinary Tract Cleansing Mix on a red surface with a pink background

Urinary Tract Cleansing Mix

This pink lemonade flushes your bladder to help prevent UTIs and protect your urinary health.

Starting at $60.00

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How do I take D-mannose for UTIs?

There are a few different ways to take D-mannose for urinary tract infection prevention. Choosing the one that’s best for you depends on your goals and needs! But, it’s important to note that these supplements are intended for UTI prevention, not treatment. And if you already have an infection? Don’t worry, we’ve got you covered with online prescription UTI antibiotics. 😘

Prevention before a known UTI trigger: If you’ve had a UTI before, there’s a good chance you have an idea what caused it! UTI triggers can include beach vacations with wet bathing suits, holding in your pee til the next road trip rest stop, or steamy summer encounters. 👀

So! If you know you’re about to do something that’s given you a UTI before—go ahead and prevent it! Wisp’s D-mannose capsule option does just that. Take three D-mannose capsules three times a day for five days to keep your urinary tract healthy, happy, and E. coli-free.

Daily UTI prevention: Annoying and painful news: UTI recurrence is super common. So if you’re tired of waking up to UTIs over and over again, incorporating a supplement that includes D-mannose into your daily routine might be for you!

Wisp’s Daily Urinary Tract Support supplement is full of natural, anti-inflammatory ingredients and antioxidants that will help defend your system from recurrent UTIs. Our supplement includes a daily-friendly dose of D-mannose along with green tea leaf extract, turmeric root extract, black pepper powder, and other natural goodness. Take our Daily Urinary Tract Support supplement to help keep your urinary tract healthy, happy, and bacteria-free.

Types of D-mannose for UTIs: D-mannose is available as capsules or tablets and as a powder to mix with water! Choose which form best suits your preferences and needs—just make sure you follow the dosage instructions and monitor your symptoms.

Can D-mannose cause kidney damage?

D-mannose functions by filtering through your kidneys and heading out of your urinary tract. Because of that, there is some concern that very high doses of D-mannose might cause kidney damage. Currently, there isn’t any conclusive research on D-mannose and kidney damage.

The research that does exist indicates that D-mannose is safe when taken at the recommended dose. So, always follow the directions on the product label when taking any type of supplement to avoid adverse effects. And, important to note: Wisp’s Daily Urinary Tract Support includes a small amount of D-mannose, but it also features other incredible ingredients proven to support urinary tract health.

And, speaking of kidney health—the bacteria from an untreated UTI can keep climbing up your system and eventually cause a kidney infection. Serious kidney infections can definitely damage your kidneys—so take care of your UTI as soon as you start feeling symptoms!

Best UTI preventative care

Story time: Once, I got a UTI while on a week-long camping trip. My symptoms didn’t feel that bad and I didn’t want to bug my friends to leave the wilderness to go find a doctor’s office. A few days in, my back started hurting–but I was camping! So it was obviously from sleeping on the ground, right? Nope! My back hurt from a UTI-turned-kidney infection. Whoops!

Luckily, there are plenty of easily accessible, over-the-counter options to keep UTIs from getting in the way! Wisp’s Daily Urinary Tract Support is jam-packed with superstar natural ingredients that help your urinary tract feel its best. Our daily supplement includes D-mannose and anti-inflammatory and antioxidant superstars: green tea leaf extract, turmeric root extract, black pepper fruit powder, and vitamin D for good measure.

Pair this daily UTI prevention supplement with probiotics and boric acid and you’ll be a triple-threat of urinary tract health. Alright, you triple-threat you: stay hydrated, pee after sex, and you’re doing great. 💟

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