Tube of estradiol cream on a red surface with a pink background
Tube of estradiol cream on a red surface with a pink background
Graphic featuring a model holding Estradiol Cream with info about the product on a pink background
Chart comparing Estradiol Cream to Harmonizing Lube

Estradiol Vaginal Cream

Reviews Trustpilot

Prescription vaginal dryness relief
This hormonal cream soothes vaginal dryness caused by menopause, or during postpartum, especially with breastfeeding. More than just your basic lubricant, our vaginal estrogen cream helps rejuvenate vaginal tissue when used over time to reduce day-to-day discomfort and help you enjoy pain-free intimacy again.

Note: Do not use with latex condoms—oil base may affect condom efficacy.

Starting at $20.00

Choose a One-Time Treatment or Subscription

How to treat vaginal dryness

The hormonal changes that occur during and after menopause can lead to uncomfortable vaginal dryness, as well as an increase in UTI symptoms and discomfort or pain during sex.

In fact, research suggests that 84% of women experience genitourinary syndrome of menopause, a chronic, progressive, vulvovaginal, sexual, and lower urinary tract condition that causes a variety of uncomfortable symptoms, including vaginal dryness and UTI symptoms. Additionally, 55% of post-menopausal women experience recurring UTIs.

Treatment with vaginal estrogen can be an effective way to address the root cause of recurring UTIs and dryness by improving the quality of vaginal tissue and preventing future infections!

Treat symptoms caused by postpartum and menopause

  • Increased UTIs & UTI symptoms
  • Vaginal dryness
  • Painful sex
  • Vaginal discomfort & itching

Medication Details

Estradiol FAQ

Your Provider

Dr. Elizabeth Swenson

Estradiol Cream is a safe hormonal option for addressing uncomfortable symptoms during menopause and postpartum.

Elizabeth Swenson, MD

How It Works


Explore Care Options

Get the care you need on your terms. Feeling unsure? Let our Symptoms Quiz guide you.

Our Experts Review

If needed, a licensed medical provider will follow up same day by phone or secure chat to ensure you receive safe and effective care.

Same-Day Pickup | FREE Delivery

Get your prescription sent to your pharmacy same day or have your care shipped FREE to your home in discreet packaging.

Our Doors Are Always Open

Chat with our Care Team anytime. We’ve got your back.