Skip to main content

Cold Sore Treatment & Care

Fast relief. Ongoing care. No shame.

Prescription antivirals for outbreaks, daily routines if yours keep coming back, and supplemental support for everything in between. No in-person waiting room. 100% online & on your terms.

Subscribe for consistent, convenient care & save up to 60%!

A close up of a woman with brown hair and a nose piercing

Cold Sore Medicine: Prescription and Supplements

A female doctor wearing a white lab coat and surgical gloves is talking on her phone

First Herpes Outbreak Consult | Valacyclovir & Acyclovir

$65

Prescription antivirals for a first-time herpes outbreak

A Wisp pill vial on a cream surface
Save up to 60%

Valacyclovir (Valtrex) or Acyclovir | HSV-1

Starting at $10/ month

Prescription antiviral pills used to prevent & treat outbreaks.

A white cream swatch on a cream surface

Lidocaine-Amitriptyline Cream | HSV-1 & HSV-2

Starting at $30

Prescription cream used to relieve oral (cold sores) and genital herpes outbreak pain.

Bottle of Acyclovir cream in someone's hand with a cream backgroound
Save up to 30%

Acyclovir Cream for Cold Sores | HSV-1

Starting at $30

Experience relief from cold sore symptoms with our prescription antiviral cream that not only alleviates discomfort but also accelerates the healing process.

Lysine capsules on cream background
Save up to 30%

L-Lysine Cold Sores | HSV-1

Starting at $27

L-Lysine is an over-the-counter medication used to manage the severity of oral & genital outbreaks.

A woman wearing white clothing is moving outdoors with motion blur

Herpes Quiz: Online Treatment & Diagnosis for Oral & Genital Herpes

Starting at $10/month

Not sure where to start? Take the quiz to find out if it's herpes and checkout with the treatment of your choice.

Stacked AV Defender pills on a cream surface

AV Defender Herbal Supplement for HSV-1 & HSV-2

Starting at $27

Boosts immunity to help reduce oral (cold sores) and genital herpes outbreaks.

A Wisp diagnostics box with sample collection supplies on a cream surface

Herpes (HSV) Test

Genital
Oral (Cold Sores)

$169

At-home HSV-1 and HSV-2 testing, made simple—swab, ship, and treat. Consult and treatment included if necessary.

A Wisp diagnostics box with sample collection supplies on a cream surface
Most Extensive

9-Panel STI Test

Chlamydia
Gonorrhea
Trichomoniasis
Syphilis
Hepatitis C
Hepatitis B
HSV-1
HSV-2
HIV

$249

The comprehensive at-home testing kit that covers 9 sexually transmitted infections, including herpes.

How to Treat a Cold Sore

Cold sores are painful blisters that pop up around your lips or mouth—once you've had one, you know how quickly they can derail your day. Just a single sore can count as an outbreak, but multiple sores are common, especially during your first outbreak.

Prescription antivirals can help when started within 24 to 48 hours of your first symptoms, ideally at the first sign of tingling. A provider can review whether one is appropriate for you.

Depending on clinical approval, we may also provide a prescription to keep on hand, so the next time a cold sore flares up, you're ready.

Cold Sore Symptoms

  • Painful blisters on the mouth, lips, nose, or throat
  • Fever and body aches (similar to flu symptoms) at the first outbreak
  • Mouth and throat pain
  • Blisters that eventually pop and scab over
  • Cold sore symptoms last about 12 days
  • Swelling in the neck
Cold sore treatment, on your schedule

Manage cold sores with prescription antivirals reviewed by a licensed provider, which can help shorten an outbreak when started early. Bye-bye in-person waiting room.

Free, discreet cold sore medication delivery

Meds ship free in (discreet) packaging. Now use all that time you saved where it really counts.

Prescription cold sore medicine for recurring outbreaks

If outbreaks keep coming back, a provider can set you up with a daily antiviral routine, if medically appropriate.

Your judgment-free cold sore care

Message the Wisp care team 24/7 from anywhere. Get access to hassle-free, judgment-free cold sore care.

Cold Sore Medicine FAQs

Reviews

4.3
out of 5
Write a Review
The comments you share will be public.

View All Wisp Company Reviews