Clear Up! Acne Cream on a red surface, on a pink background
Clear Up! Acne Cream on a red surface, on a pink background
Woman's hand reaches for glass of water next to Wisp Skincare bottles on her bedside table
Woman looks at clear skin in the mirror
Woman's hand reaches for Wisp skincare bottles with colorful geometric shapes

Clear Up! Acne Cream (Clindamycin + Retin A)

Reviews Trustpilot

Prescription strength acne fighter

OTC acne treatments can only take you so far. When your skin needs a little extra support, our Clear Up! Acne Cream is here with effective, prescription strength Clindamycin + Tretinoin (Retin A). Banish inflammation, pimples, and clogged pores and get clear.

*Do not use in addition to Wisp's Wrinkle Cream

FSA & HSA accepted.

Starting at $75.00

Choose a One-Time Treatment or Subscription

Acne Overview

Acne isn't just a problem for hormonal teens — plenty of us deal with inflammation, redness, and zits as adults. It can be hard (and expensive) to find ingredients that actually work. Our Acne Cream includes tried-and-true prescription strength ingredients. Clindamycin targets inflammation to reduce pain and redness, tretinoin boosts cell turnover to reveal clear skin fast, and niacinamide works to smoothe and repair. Apply 1 pump of our Acne Cream every night before bed to start seeing the acne-fighting results!

Browse all skincare treatments

Acne Symptoms

  • Whiteheads
  • Blackheads
  • Small red, tender bumps
  • Pimples (pustules)
  • Large, solid, painful lumps
  • Painful, pus-filled lumps

Medication Details

Acne Treatment FAQ

Your Provider

Dr. Marc Serota

Wisp's Acne Cream is formulated by dermatologists to outperform any product that's available over the counter for treating acne quickly and effectively.

Dr. Marc Serota, M.D.

How It Works


Choose Your Meds

Decide what's right for you and complete a quick (private) medical form. Select a one-time or recurring-subscription plan.

Our Doctors Review

Within 24 hours, a U.S. licensed physician will follow up by phone or secure chat and write a prescription (when safe and appropriate).

Free Delivery | Same day Pickup

Meds ship FREE to your home in discreet packaging, or you can pick them up same-day at a local pharmacy.