Firm Up! Wrinkle Firming Cream on a red surface, on a pink background
Firm Up! Wrinkle Firming Cream on a red surface, on a pink background
Woman's hand reaches for glass of water next to Wisp Skincare bottles on her bedside table
Woman looks at clear skin in the mirror
Woman's hand reaches for Wisp skincare bottles with colorful geometric shapes

Firm Up! Wrinkle Cream | Tretinoin (.04%)

Reviews Trustpilot

Create your own afterglow

Too busy to capture that post-O glow the old-fashioned way? Have it 24/7 with our Firm Up! Tretinoin Cream (0.04%). Smooth out wrinkles and firm your skin for a more radiant look at any age, with or without the O.

*Do not use in addition to wisp Acne Cream

Love Your Skin

Your skin does a lot for you — we think it's time to return the favor. Tretinoin increases cell turnover and thickens your skin barrier which helps to smooth out fine lines and wrinkles, reduce acne, and lighten dark spots. Faster cell turnover also means fresher, glowing skin. One pump at bedtime is all you need, but be sure to always apply a sunscreen with an SPF of at least 30 when using tretinoin — it makes your skin more sensitive to UV rays. Get glowing.

Browse all skincare treatments

Tretinoin Applications

  • Fine wrinkles
  • Spotty discoloration
  • Acne

Medication Details

Tretinoin FAQ

Your Doctor

Dr. Marc Serota

Tretinoin is the most effective ingredient when it comes to real anti-aging results. It is safe to use long term and not only helps address wrinkles and fine lines today, but with consistent use, many patients will protect against signs of future aging.

Dr. Marc Serota, M.D.

How It Works

1
Choose Your Meds
Decide what's right for you and complete a quick (private) medical form. Select a one-time or recurring-subscription plan.
2
Our Doctors Review
Within 24 hours, a U.S. licensed physician will follow up by phone or secure chat and write a prescription (when safe and appropriate).
3
Free Delivery | Same day Pickup
Meds ship FREE to your home in discreet packaging, or you can pick them up same-day at a local pharmacy.