Estradiol (Cream) - 1 Tube - 42.5g
Prescription vaginal dryness relief.
This hormonal cream soothes vaginal dryness caused by menopause, or during postpartum, especially with breastfeeding. More than just your basic lubricant, our vaginal estrogen cream helps rejuvenate vaginal tissue when used over time to reduce day-to-day discomfort and help you enjoy pain-free intimacy again.
Eligible estradiol patients are 40+, breastfeeding, and at least one year postpartum.
Note: Do not use with latex condoms—oil base may affect condom efficacy.
FSA & HSA accepted.
How It Works
Estradiol FAQ
Wisp Care Team

Estradiol cream is a gentle, targeted way to treat vaginal dryness, irritation, and discomfort during menopause or postpartum. It’s low-dose, effective, and works with your body to restore balance right where you need it most.




