Question 1

Does Zofran make you sleepy?

Accepted Answer

Drowsiness is a possible side effect of Zofran, but overall, it's rare to experience side effects with Zofran.

Question 2

What is Ondansetron?

Accepted Answer

Ondansetron is the generic form of Zofran—it contains the same active medication as Zofran for a more affordable price.

Question 3

When should I take Zofran?

Accepted Answer

If you're taking Zofran to prevent nausea caused by medication, you can take one Zofran tablet 30 minutes before your prescribed dose of medication, which allows for enough time for the Zofran to kick in and prevent those uncomfortable waves of nausea. Keep in mind that the maximum dose of Zofran is one pill, three times daily every 8 hours. Taking Zofran with antibiotics, for example, can help you reduce your side effects so you can finish your medication and prevent your infection from returning.

Question 4

Does Zofran have side effects?

Accepted Answer

Side effects with Zofran are rare, but it is possible to experience mild side effects such as:
Constipation
Headache
Drowsiness
Diarrhea
One important benefit is that Zofran can be taken with or without food! It can be hard to eat when you are feeling nauseous, so don’t feel pressure to eat before taking it. You will tolerate it just fine!

Question 5

Who should not take Zofran?

Accepted Answer

While Zofran is generally well tolerated, and extremely helpful when experiencing nausea after starting a new medication, there are some drug interactions you’ll want to watch for.
Zofran is a **serotonin receptor blocker**—if serotonin receptors are blocked, there will be more serotonin circulating around your body. An increase in circulating serotonin can be dangerous because there are other medications that allow for increased serotonin in your body—medications that help with anxiety, depression **(SSRI’s)**, migraine medications **(Triptans)**, and antibiotics like **Linezolid**. If you are on one of the mentioned medications while taking Zofran, you may be putting yourself at risk for **Serotonin Syndrome**, a condition that occurs when your serotonin levels are dangerously high. This syndrome can have mild symptoms such as experiencing shakiness, trouble sleeping, excessive sweating. More extreme symptoms are high fever, uncontrollable diarrhea, and uncontrollable shaking and body movements. Of note, if any of those side effects are to occur while taking Zofran, please stop taking the medication and seek medical attention immediately.
Additionally, while cardiac side effects are definitely rare with Zofran, there are some reports of QT elongation when taking this medication, which is quite dangerous causing the heart to take longer to contract and relax. Who is at risk for this? Those who are taking **antiarrhythmic medication**, people with **low potassium or magnesium levels**, those who take antibiotics from the Fluroquinolone family **(Ciprofloxacin, levaquin)**, or Macrolide family **(Azithromycin)**.
If you have a history of the below mentioned conditions, you should speak to your medical provider before taking Zofran:
Heart disease
History of irregular heartbeat
Liver disease
Low levels of magnesium or potassium in the blood
An unusual or allergic reaction to ondansetron, granisetron, other medications, foods, dyes, or preservatives
Pregnant or trying to get pregnant
Anxiety/depression and on SSRI’s
History of PKU
Breastfeeding

Question 6

Does Zofran work for motion sickness?

Accepted Answer

Zofran is not recommended for motion sickness. Ginger or Dramamine are still the best treatments for nausea caused by motion sickness, so be sure to include them alongside Zofran for complete protection from planes, trains, automobiles, and boats.

Question 7

Can I take Zofran with alcohol?

Accepted Answer

Do not take this drug with alcohol, marijuana, or other recreational drugs. Wait until alcohol is out of your system before taking Zofran.

Question 8

What information do I need to provide after placing my order?

Accepted Answer

Patients need to provide the following so our providers can verify that treatments will be safe and effective:
A current/ valid form of ID
Height and weight
A list of current medications
A list of any drug allergies
A list of current diagnoses or conditions for taking prescriptive medications
For hormonal treatments, patients may need to provide:
Blood pressure readings taken within the last year (required for combination birth control pills)
The date of your last menstrual period
_Disclaimer: Additional lab and/or diagnostics (like photos) may be required based on treatment request_

Zofran (Ondansetron)